The Plan:
- Do an egg retrieval.
- Take resulting embryos and the three frozen embryos we have leftover and grow them until they are 5 days old.
- At five days, see if they have become blastocysts.
- At five days if we have 3 or fewer blastocysts, just tranfer them then without genetic testing.
- At five days if we have 4 or more blastocysts, send them for testing and freeze them, doing the transfer in a different cycle.
Reasons for plans to grow Embryos to Blastocyst instead of transfering at day 3 as we usually do:
- I only wanted to do ONE MORE transfer. Over this. So over it.
- To maximize chance of pregnancy and minimize risk of miscarriage. See following bullets.
- Would like to test embryos before transfer to transfer only healthy ones, making another miscarriage far less likely.
- Blastocysts have slightly higher chance of implantation than 3-day embryos.
Risks of this plan:
- Many embryos will not grow to blastocyst outside the body, so you will always lose some.
- The ones you lose are not necessarily "bad ones" that wouldn't have worked at day 3.
- The one time we tried to do this before none of our 6 embryos made it to blastocyst.
How it Went
This Egg Retrieval:
- 20 eggs
- 16 mature
- 15 fertilized
Eggs Retrieved from my ovaries so far:
Eggs Retrieved from my ovaries so far that have become human babies:
This cycle's embryos on Day 3:
- 15 fresh +
- 3 frozen and thawed =
- 18 day 3 embryos
Embryo Quality on Day 3:
Fresh:
First number = scale of 1-4 looking at fragmentation.
1=excellent, 2=above average, 3=average, 4=below average
Second number = number of cells, with at least 6 cells being a great number.
- 2 8
- 2 10
- 2 9
- 2 8
- 3 6
- 3 8
- 2 8
- 2 8
- 3 5
- 2 6
- 2 8
- 4 7
- 2 8
- 2 8
- 4 5
Thawed:
"excellent" with the following numbers of cells
Stages for an embryo to go through before becoming a blastocyst:
- plain old embryo
- morula
- early blastocyst 1
- early blastocyst 2
- blastocyst
What stage embryos need to be in to be genetically tested (by Day 6) OR to have a decent chance of resulting in a pregnancy if transfered on Day 5:
Embryos morning of day 5:
- 8 - morula
- 8 - early blastocyst 1
- 2 - dead/plain old embryo/not mentioned so who knows
Difficult decision:
- Transfer the three best that afternoon, although a very low likelihood of resulting pregnancy, and a risk of genetically unhealthy embryo becoming a pregnancy. If we wait, there may be none to send for testing, and we would get not a single transfer/chance. Dr. feels unlikely any will make it to blastocyst. This retrieval was particularly painful (still in pain a week and a half later) and I would regret not even getting one try out of it or at least knowledge that they aren't healthy and thus aren't worth transfering.
Best 3 embryos at time of transfer on day 5:
- blastocyst!
- blastocyst!
- early embryo 2
Difficult decision 2 of the day:
- go through with the transfer anyhow because still not enough to make it worth genetic testing and still not looking promising that more will grow. A gamble, with the downside being that we, again, still don't know about the genetic health of embryos, hence risk another miscarriage.
- Transfered 3 embryos - Friday July 18th - day 5
Embryos morning of day 6:
- 3 = blastocysts - sample cells sent off for testing and then embryos frozen and waiting
- 12 = not blastocysts -sent to wherever bad embryos go
- 3 = in my uterus so who knows
Final Thoughts:
- Of course, had I know that 3 more would be champs, I wouldn't have had the transfer on day 5. Would way rather have sent 5 or 6 off for testing and tranferred only healthy ones in one transfer.
- But we made the best decisions with what we knew.
- If the ones inside me do not result in a child, and any of the 3 sent for testing are healthy (we will know in about a week) then I will likely do another fucking transfer.
Next Steps if None of that Works:
- We have a lot of thinking to do and I don't feel like sharing publicly where we are with all of that yet, as we are really in a state of flux in terms of where we want to go next. Far less sure than we felt before about further plans.
- If you know a good Bay Area therapist who specializes in Infertility, let me know.